Pharmaceutical Industry Cooling Solutions

Falling Film Chillers for Pharmaceutical Processes

In the pharmaceutical industry, falling film chillers are essential for sterile and efficient cooling in drug production. These systems optimize heat transfer, providing rapid cooling while upholding the highest standards of purity and safety.

Falling film chillers are designed to cool pharmaceutical media precisely and hygienically. A thin film of liquid flows over vertical tubes as refrigerant evaporates inside, offering high-efficiency indirect cooling without contamination risks. They manage critical temperature needs in processes like fermentation, crystallization, lyophilization, or API synthesis. Their ability to handle phase changes, maintain sterility, and facilitate energy recovery makes them indispensable in pharma.

Falling film chillers support cooling, condensation, solvent recovery, and thermal control in pharmaceutical manufacturing. Built with materials meeting GMP and 3-A Sanitary Standards, including sanitary designs, these chillers ensure scalability and ease of maintenance for seamless integration into pharma systems.

Pharmaceutical Cooling Solutions Producing safe and effective pharmaceuticals requires advanced cooling to preserve efficacy and comply with regulations. HeatX leads in pharmaceutical cooling with tailored falling film chillers for your sterile needs.

Fermentation and Bioprocessing: Falling film chillers maintain optimal temperatures for microbial growth and product stability in biotech processes.

Condensation: Vapors from distillation are condensed sterilely into liquids for recovery using falling film technology.

Lyophilization Support: Precise cooling aids freeze-drying, preserving drug potency.

Energy Recovery: Chillers recover heat between stages, enhancing efficiency and reducing costs.

Solvent Handling: Pharmaceutical solvents are chilled hygienically for extraction or purification.

API Cooling: Active ingredients are cooled efficiently in sterile environments to prevent degradation.

Pharmaceutical processing equipment
Shell & Tube:
Pharmaceutical Applications
  • Evaporators & Condensers
  • Sanitary & Corrosion-Resistant
  • Stock and Custom Models Available
Shell and Tube
Plate & Frame:
Pharmaceutical Applications
  • Fully Customizable
  • Multiple Materials Available
  • Easy Service and Maintenance
Plate and Frame
Brazed Plate:
Pharmaceutical Applications
  • Compact Form Factor
  • Multiple Materials Available
  • Various Connections
Embossed Plate
Tube-in-Tube:
Pharmaceutical Applications
  • Fully Customizable
  • High Temperature & Pressure
  • Temperature Crossing
Tube-in-Tube

Falling film chillers are vital in pharmaceutical processing for sterile cooling near freezing without ice buildup. They ensure precise temperature control in fermentation, lyophilization, and API synthesis, boosting efficiency. These chillers support solvent recovery and comply with GMP for safe, high-quality drug production.

Common chiller types in the pharmaceutical industry include:

  • Shell and Tube Chillers: Offer sterile control and durability for large-scale pharma processing.
  • Plate Heat Chillers: Ideal for hygienic heat transfer and CIP cleaning in sterile environments.
  • Falling Film Chillers: Provide efficient cooling for sensitive pharma fluids under sanitary conditions.

Stainless steel (e.g., 316L) and sanitary alloys are optimal for falling film chillers in pharma due to their corrosion resistance and sterility. These materials comply with GMP, withstand cleaning agents, and prevent contamination in drug production.

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